Scientist, R&D

<p class=""p1"">Here at Glaukos, we recognize the deep significance and profound meaning that comes from knowing that we can make a meaningful difference by helping improve the eyesight of people worldwide. Because we&rsquo;re a rapidly growing company with a dynamic, fast-paced culture, employees here are empowered with more diverse and enriching challenges than might not be possible at a larger company.</p>

Aliso Viejo, CA

Glaukos

<h4>Founded in 1998, Glaukos Corporation is an ophthalmic medical technology and pharmaceutical company focused on novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases.</h4> <h4>Our company was the first company to bring to market Micro-Invasive Glaucoma Surgery (MIGS), the micro-invasive procedure which revolutionized the treatment and management of glaucoma. In 2012, we launched our first MIGS device&mdash;the iStent&reg;&mdash;in the United States, followed by our next-generation iStent&nbsp;inject&reg;&nbsp;device in September 2018 and iStent&nbsp;inject&reg;&nbsp;W in September 2020.</h4> <h4>In November 2019, Glaukos acquired Avedro, maker of the first and only FDA-approved cross-linking technology for progressive keratoconus. And we continue to seek to leverage our platform technologies to build a comprehensive and proprietary portfolio of micro-scale surgical and pharmaceutical therapies for glaucoma, corneal health, and retinal diseases.</h4> https://www.glaukos.com/

keywords: about glaukos,position summary,training,troubleshoot & provide support,duties,evaluate,education experience,knowledge,communication

Full time

Overview: <h4 class="job-details__description-header text-color-secondary font-family-secondary" data-bind="i18n: 'job-details.employer-description-title'"><strong>ABOUT US</strong></h4> <div class="basic-formatter" data-bind="html: job().corporateDescription"> <h4>Founded in 1998, Glaukos Corporation is an ophthalmic medical technology and pharmaceutical company focused on novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases.</h4> <h4>Our company was the first company to bring to market Micro-Invasive Glaucoma Surgery (MIGS), the micro-invasive procedure which revolutionized the treatment and management of glaucoma. In 2012, we launched our first MIGS device&mdash;the iStent&reg;&mdash;in the United States, followed by our next-generation iStent&nbsp;<em>inject</em><sup>&reg;</sup>&nbsp;device in September 2018 and iStent&nbsp;<em>inject</em><sup>&reg;</sup>&nbsp;W in September 2020.</h4> <h4>In November 2019, Glaukos acquired Avedro, maker of the first and only FDA-approved cross-linking technology for progressive keratoconus. And we continue to seek to leverage our platform technologies to build a comprehensive and proprietary portfolio of micro-scale surgical and pharmaceutical therapies for glaucoma, corneal health, and retinal diseases.</h4> <h4>Our company completed an initial public offering in June of 2015, and our shares are traded on the New York Stock Exchange under the ticker symbol &ldquo;GKOS&rdquo;. Our global headquarters is located in San Clemente, California with additional locations in Waltham and Burlington, Massachusetts.</h4> <h4 class="job-details__description-header text-color-secondary font-family-secondary" data-bind="i18n: 'job-details.job-description-title'"><strong>JOB DESCRIPTION</strong><br /><br />Provides technical expertise to perform and implement analytical development activities to support all stages of drug development and solve challenging analytical problems.&nbsp;</h4> </div>
Responsibilities: <ul> <li>Participates in bench-level drug product stability testing and release of test articles, generating accurate and precise data using advanced analytical technologies.</li> <li>Troubleshoots, provides analytical support for investigations studies and solves analytical issues in timely manner, ensures generation of high-quality scientific data.</li> <li>Evaluates and interprets analytical results from release and stability studies and provides scientific conclusions.</li> <li>Has hands-on and direct expertise in analytical methodologies used for the characterization of drug delivery systems and protein formulations for drug release, potency, biological activity, stability, impurity testing and aggregation profile. Demonstrate method suitability for applications to drug product development.</li> <li>Prepares experimental protocols and well written technical reports in support of regulatory submissions. Provides training and guidance to chemists/scientists in the team.</li> <li>Represents as analytical lead on CMC project teams and contributes to team discussions. Support QC department with establishing robust methods, product specifications, method validations and method transfers.</li> <li>Proactively develops and maintains knowledge in current analytical sciences and investigates new technology and recommends innovative techniques to the team.&nbsp;Maintain strong working knowledge of ISO/GLP/GMP compliance.</li> <li>Plus, other duties as assigned by management</li> </ul>
Requirements: <ul> <li>M.S. (4+ years) or B.S. (6+ years) in analytical chemistry, pharmaceutical chemistry, pharmaceutical sciences, or related scientific field and 3+ years of pharmaceutical industry experience in the method validation and analytical testing of drug products.</li> <li>Strong hands-on knowledge of advanced chemical analysis principles, chromatographic theories and technologies.</li> <li>Working knowledge of a wide range of analytical methods (i.e., HPLC, UPLC, GC, dissolution, LC-MS, UV/Vis), and other common analytical techniques used to determine potency, purity, and in-vitro performance of drug substance and drug product.</li> <li>​​​​​​​​​​​​​​Ability to lead investigations and troubleshoot analytical related problems at all stages of development.</li> <li>Experience in oversight of stability studies and conducting trend analysis.</li> <li>Experience working in a cGMP analytical laboratory is required.</li> <li>Demonstrated ability to learn (new technologies, methodologies etc.)</li> <li>Experience in interacting with pharmaceutical CROs and CMOs.</li> <li>Strong ability and knowledge to develop, validate and transfer analytical methods.</li> <li>Knowledge of Quality systems, Drug Product Manufacturing and Validation.</li> <li>Excellent verbal communication, strong writing skills, and being detail and result oriented are important attributes.</li> <li>Working knowledge of drug development and drug substance and drug product regulations, including relevant USP, FDA and ICH regulatory requirements and guidance documents for analytical testing and stability assessments.</li> </ul> <br /> <p>We offer competitive salary (based on experience), bonus eligibility, medical/dental/vision, life insurance, stock options, 401(k) Employer Match, Employee Stock Purchase Program, generous time off &amp; paid holidays as well as time-off to volunteer in the community, plus the opportunity to work for a company that is pioneering a new glaucoma treatment class! Glaukos Corporation has been Certified as a Great Place to Work the last two years!&nbsp;</p> <p>Glaukos Corporation is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.&nbsp;</p>